von Hippel-Lindau disease - traducción al ruso
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von Hippel-Lindau disease - traducción al ruso

A RARE GENETIC DISORDER CHARACTERIZED BY VISCERAL CYSTS AND BENIGN TUMORS IN MULTIPLE ORGAN SYSTEMS WITH POTENTIAL FOR SUBSEQUENT MALIGNANT CHANGE.
Von Hippel-Lindau Disease; Von Hippel-Lindau syndrome; VHL syndrome; VHL disease; Hippel-lindau disease; Cerebelloretinal Angiomatosis, familial; Angiomatosis retinae; Von Hippel-Lindau; Von Hippel Lindau; Von Hippel Lindau syndrome; Vhld; Von Hippel–Lindau syndrome; Von Hippel-Lindau disease; Von Hippel – Lindau syndrome; Angiomatosis retinate; Lindau-von Hippel disease; Lindau’s disease; Lindau's disease; Von Hippel-Lindau's disease; Von Hippel – Lindau disease; Von Hippel - Lindau syndrome; Von Hippel - Lindau disease; Von Hippel–Lindau Disease; Von Hippel–Lindau
  • The regulation of HIF1α by pVHL. Under normal oxygen levels, HIF1α binds pVHL through 2 hydroxylated proline residues and is polyubiquitinated by pVHL. This leads to its degradation via the proteasome. During hypoxia, the proline residues are not hydroxylated and pVHL cannot bind. HIF1α causes the transcription of genes that contain the hypoxia response element. In VHL disease, genetic mutations cause alterations to the pVHL protein, usually to the HIF1α binding site.
  • Original Von Hippel's description of disease
  • Typical distribution of hemangioblastomas in Von Hippel–Lindau disease.
  • [[Slit lamp]] photograph showing [[retinal detachment]] in Von Hippel–Lindau disease

von Hippel-Lindau disease         

медицина

болезнь Гиппеля-Линдау

Hippel-Lindau disease         

медицина

ангиофакоматоз

heterogenesis         
  • X-ray of Kölliker's hand, made by Röntgen on 23 Jan 1896
SWISS ANATOMIST, PHYSIOLOGIST (1817–1905)
Albert von Kolliker; Koelliker; Rudolf Albert von Kolliker; Rudolf Albert von Kölliker; Albert von Koelliker; Rudolph Albert von Kolliker; Rudolf von Kölliker; Albert Kolliker; Rudolph Albert von Kölliker; Rudolf von Kolliker; Rudolph Albert von Koelliker; Rudolf Albert von Koelliker; Rudolf von Koelliker; Kolliker; Heterogenesis; Rudolf Albert Koelliker; Rudolf Albert Kölliker; Albert Koelliker; Albert Kölliker; Koell.; Kölliker

[het(ə)rə(u)'dʒenisis]

общая лексика

гетерогенез

чередование поколений

медицина

гетерогония

существительное

биология

гетерогенез

Definición

ЕВГЕНИЙ САВОЙСКИЙ
(Eugen von Savoyen) (1663-1736) , принц, австрийский полководец, генералиссимус (1697). В 90-х гг. 17 в. нанес ряд поражений французским войскам в Италии, одержал победы над турками (1697, 1716), над французскими и франко-баварскими войсками во время войны за Испанское наследство (в т. ч. при Мальплаке), но потерпел поражение при Денене. С 1703 председатель военного, затем тайного совета при императоре.

Wikipedia

Von Hippel–Lindau disease

Von Hippel–Lindau disease (VHL), also known as Von Hippel–Lindau syndrome, is a rare genetic disorder with multisystem involvement. It is characterized by visceral cysts and benign tumors with potential for subsequent malignant transformation. It is a type of phakomatosis that results from a mutation in the Von Hippel–Lindau tumor suppressor gene on chromosome 3p25.3.

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